Iodine: The Natural Solution Supplemental Protocol for Total Body Health

Orthoiodosupplementation is the daily amount of the essential element iodine needed for whole body sufficiency. Whole body sufficiency for iodine is assessed by an iodine/iodide loading test. The test consists of ingesting 1 tablet of a solid dosage form of Lugols solution, containing a total of 50 mg iodine/iodide. Then urinary iodide levels are measured in the following 24 hour collection. The iodine/iodide loading test is based on the concept that the normally functioning human body has a mechanism to retain ingested iodine until whole body sufficiency for iodine is achieved. During orthoiodosupplementation, a negative feedback mechanism is triggered that progressively adjusts the excretion of iodine to balance the intake. As the body iodine content increases, the percent of the iodine load retained decreases with a simultaneous increase in the amount of iodide excreted in the 24 hour urine collection. When whole body sufficiency for iodine is achieved, the absorbed iodine/iodide is quantitatively excreted as iodide in the urine. In the U.S. population, the percent of iodine load excreted in the 24 hour urine collection prior to orthoiodosupplementation averages 40% in more than 7,000 loading test performed by Dr. Jorge Flechas.

After 3 months of supplementation with 50 mg LugoTab per day, most non-obese subjects not exposed to excess goitrogens achieve whole body iodine sufficiency, arbitrarily defined as 90% or more of the iodine load excreted in the 24 hour urine collections. Adult subjects retained approximately 1.5 grams of iodine when they reach sufficiency. A repeat loading test following 3 months on orthoiodosupplementation is recommended.

The goal of orthoiodosupplementation is not the treatment of disease, but the supply of optimal amounts of an essential nutrient for whole body sufficiency and for optimal mental and physical performances. Whole body sufficiency for iodine correlates well with overall wellbeing, and some subjects could tell when they achieved sufficiency even before knowing the results of the test. Iodine sufficiency was associated with a sense of overall wellbeing, lifting of a brain fog, feeling warmer in cold environments, increased energy, needing less sleep, achieving more in less time, experiencing regular bowel movements and improved skin complexion. Whole body iodine deficiency, based on the concept of orthoiodo- supplementation, may play an important role in several clinical conditions. Hundreds of physicians and other health care providers are now using the loading test and implementing orthiodosupplementation in their practice, using a tablet form of Lugols solution (LugoTabs). A very good correlation between the results of the loading test and clinical response of their patients to iodine supplementation was reported.

Procedure for the loading test

The test kit contains:

  • 50mg LugoTab iodine load tablet
  • 3 Liter orange urine collection jug
  • 2 vials for samples
  • 16 ounce collection cup
  • shipping material (including a prepaid return mailing label and a zip lock bag with absorption materials to be wrapped around each specimen vial before shipment).

We recommend this general outline for the 24 hour testing procedure:

  1. Discard the first morning void
  2. Take 1 tablet of LugoTab 50mg
  3. Start collection of urine, following instructions contained in the kit;
  4. The first void on the following morning should be included in the urine collection
  5. If total urine volume is above 3 Liters, follow instructions supplied with the kit.

A suggested plan for the implementation of Orthoiodosupplementation1

It is recommended that supplementation with the essential element iodine be part of a complete multinutritional program for best results. It is ideal to start this program 2 week before iodine supplementation.

Below are the recommended multivitamin/multimineral formulations:
(You can purchase each supplement individually using the “Hakala Research Product” column or you can purchase our Orthoiodo supplementation protocol and save 10%.)

Supplement Suggestions

According to Dr. Guy Abraham in his Nov. 2004 publication: The Safe and Effective Implementation of Orthoiodo- supplementation In Medical Practice the best results are obtained with a complete nutritional program which includes Iodine. The program suggests the following supplementation plan:

Hakala Research Product
Iodine & Potassium Iodide Combination
12.5mg daily for 7 days, then adjust up to
4 tablets daily
LugoTab 12.5mg -180 tablets
LugoTab 12.5mg -90 tablets
Vitamin B2 & B3 complex, slow release
B2 (Riboflavin) AND
B3 (Inositol Hexanicotinate)

100mg &
200mg/day &
ATP Boost
Vitamin C, slow release
(Ascorbic Acid)
(Magnesium Oxide)
**If your daily multi-vitamin contains Selenium, additional supplementation is not
Sea Salt
1 tsp daily
1 tsp daily
Celtic Sea Salt-Fine Ground
Celtic Sea Salt-Coarse Ground

Bromide testing

In addition to the Iodine testing, we also offer Bromide testing to determine if this toxic goitrogen is present in the body. Excessive Bromide levels can lead to decreased thyroid function as well as general body fatigue. Click here for our ongoing list of bromide sources.

Iodine Reference Articles:

  • Abraham, G.E. Facts about Iodine and Autoimmune Thyroiditis The Original Internist, 2008.

Boron Reference Articles

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