Here is an in depth, two year study regarding Lithium Orotate conducted by H. A. Nieper of Silbersee Clinic.  "The specific principle is considered to be a directed intracellular transportation of lithium by means of the orotic carrier molecule, which has a high affinity for tissue dependent on the blood brain barrier.  The directed carrier principle of the lithium orotate therapy makes a determination of the lithium level in blood serum unnecessary.  The effectiveness of lithium therapy as such is based on a membranal and cellular displacement of sodium."

Also, the article, "The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis" is an interesting discussion regarding lithium and putative therapeutics to slow the progression of neuronal loss.

Hakala Research formulates and manufactures Lithium Orotate in a 10mg tablet.  Click to purchase.